About my work....
Until July 2005 I worked in the Human Genome Sequencing Center
at Baylor College of Medicine, officially as a Computer Programmer II;
unofficially, and more importantly, as a Troubleshooter for sequence data flow, in addition to work with research projects in comparative genomics.
From 1991 through June of 2000, I
worked as a biologist and webmaster for the Molecular Biology
Computation Resource, also at Baylor College of Medicine.
I was a post-doc in the laboratory of Lawrence Chan in the Cell Biology Department (now known as the Department of Molecular and Cellular Biology) for a year and a half, before that.
If you're interested in dye
chemistry, oxygen radicals, the
photodynamic effect, and DNA damage, you can see my
Ph.D. thesis at Rice University (in a non-searchable, slightly croooked image representation), with all figures and images, or you can see a
text-readable version on this site that is missing some figures. I graduated in 1989 from Rice
University, the last Ph.D. from their Biology Department before it
underwent reorganization, whereupon my part joined the Biochemistry Department.
- The finished DNA sequence of human chromosome 12. Nature. 2006 Mar 16;440(7082):346-51.[I am number seventy-seven in the list of authors - see the abstract on PubMed.]
- The DNA sequence of the human X chromosome.
Nature. 2005 Mar 17;434(7031):325-37. [I am number sixty-seven in the list of authors.]
- Finishing the euchromatic sequence of the human genome.
International Human Genome Sequencing Consortium. Nature 431, 931 - 945 (21 October 2004).
[I am number 1,717 in the list of authors.]
- Genomic Analysis of the Nuclear Receptor Family: New Insights Into Structure, Regulation, and Evolution From the Rat Genome. Zhengdong Zhang, Paula E. Burch, Austin J. Cooney, Rainer B. Lanz, Fred A. Pereira, Jiaqian Wu, Richard A. Gibbs, George Weinstock and David A. Wheeler. Genome Research 14:580-590, 2004.
- Rat Genome Sequencing Project Consortium. Genome
sequence of the Brown Norway rat yields insights into
mammalian evolution. Nature
428, 493 - 521 (01 April 2004). [My name is tenth on the
list of authors, at the end of the paper.]
- Over two hundred thousand Genbank nucleotide sequence entries
- Initial sequencing and analysis of the human
genome. International Human Genome Sequencing Consortium. (abstract)
2001 Feb 15;409(6822):860-921 (see the huge full
author list [Microsoft Word document]).
- Li D, Burch P, Gonzalez O, Kashork CD, Shaffer LG, Bachinski LL, Roberts R.
cloning, expression analysis, and chromosome mapping of WDR6, a novel
human WD-repeat gene. [abstract] Biochem Biophys Res Commun 2000 Jul 21;274(1):117-23
- Duanxiang Li, Miguel Quinones, William Zoghbi, Linda Bachinski,
Douglas Mann, Paula Burch, Terry Tapscott, Oscar Gonzales, Rita
Hill, and Robert Roberts (1999). A desmin mutation responsible for
idopathic dilated cardiomyopathy. Circulation,
- Fouad A.K. El-Zaatari, Saleh Naser, Kristina Hulten, Paula Burch, and
David Y. Graham. Characterization of
Mycobacterium paratuberculosis p36 antigen and its seroreactivities in
Crohn's Disease. Current Microbiology vol. 39 (1999), pp 115-119.
- D.A. Wheeler, D.L. Steffen, L.F. Deretchin, J.A. Chapman, P.E. Burch, J.R. Beck and L.S. Jefferson (1996). Web-Based Tools for Medical Education Information Management. Symposium for Computer Applications in Medical Care. American Medical Informatics Association 20th Proceedings, Washington, D.C.
- D.L. Steffen, S. Yarus, P.E Burch and D.A. Wheeler (1996). A Paradigm for Electronic Publication. Symposium for Computer Applications in Medical Care. American Medical Informatics Association 20th Proceedings. Washington, D.C.
- L.F. Deretchin, P.E. Burch, J.A. Chapman, D.L. Steffen, A.
Giannotti, C.L. Seidel, L.S. Jefferson, D.A. Wheeler (1996). Web-based
Informatics Tools for Medical Education. "The Virtual Medical
School", Computers in Healthcare Education Symposium. Health
Sciences Libraries Consortium and Thomas Jefferson University,
- L.F. Deretchin, P.E. Burch, J.A. Chapman, D.L. Steffen, C.L. Seidel, L.S. Jefferson and D.A. Wheeler (1995). Web-based Informatics Tools for Medical Education. 5th Annual Retreat, Keck Center for Computational Biology. Galveston, TX.
- D.A. Wheeler and P.E. Burch (1994). Connecting Medical Researchers to Molecular Biology Information Services. Outreach as a Component of IAIMS: Library Outreach, Telemedicine, Distance Learning and Collaboratories. 6th Annual IAIMS Consortium Meeting, Yale University, New Haven, CT.
- Development of a Faculty Research Interest Resource. Jerry Fowler, David A. Wheeler, Pat W. Camerino, Olga Bat and Paula E. Burch. Baylor College of Medicine. Proceedings 1996 American Medical Informatics Association Annual Fall Symposium (Formerly SCAMC), Washington, DC. Oct. 1996, 363-367.
or PDF file of full article.)
- Nucleotide Sequence Analysis and Seroreactivities of the 65K Heat
Shock Protein from Mycobacterium paratuberculosis. Fouad A. K.
El-Zaatari, Saleh A. Naser, Lars Engstrand, Paula E. Burch, Charles Y.
Hachem, Diane L. Whipple, and David Y. Graham. Clinical and Diagnostic
Laboratory Immunology, Nov. 1995, 2(6): 657-664 [in PDF format]. (Also see MedLine abstract.)
- Production of superoxide by photosensitization. Martin, J.P., and
P.E. Burch. Methods in Enzymology 186:635-645 (1990). (See medline.)
- DNA Damage and Cell Lethality by Photodynamically Produced Oxygen Radicals. P. E. Burch. Doctoral Dissertation, Rice University, 1989.
- Oxygen radicals are generated by dye-mediated intracellular photooxidations. Martin, J.P., and P.E. Burch. In: "Oxyradicals in Molecular Biology and Pathology," I.Fridovich, J. McCord, and N. Cerutti (eds.), Alan Liss: New York. (1988).
- Protection against dye mediated photodynamic effects is conferred by DNA repair enzymes and oxygen radical scavengers. Burch, P.E., and J.P. Martin. FASEB Journal 2(4)A766 (1988)
- Oxygen Radical Generation in E. coli B by dye mediated photooxidation. Burch, P.E., and J.P. Martin, Jr. Federation Proceedings 46:1045 (1987).
Page created: July 15, 1998
Last updated: September 26, 2011
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